Cellular Biology of the Endoplasmic Reticulum

A View of the Endoplasmic Reticulum Through the Calreticulin Lens.- Structural Analysis of Calreticulin, an Endoplasmic Reticulum-Resident Molecular Chaperone.- The Role of Endoplasmic Reticulum Chaperones in Protein Folding and Quality Control.- Proteins Interacting with STIM1 and Store-Operated Ca2+ Entry.- Endoplasmic Reticulum (ER) and ER-Phagy.- Defects in Protein Folding and/or Quality Control Cause Protein Aggregation in the Endoplasmic Reticulum.- Roles of Calreticulin in Protein Folding, Immunity, Calcium Signaling and Cell Transformation.- Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and Disease.- Cancer Biology of the Endoplasmic Reticulum Lectin Chaperones Calreticulin, Calnexin and PDIA3/ERp57.- Maintenance of Endoplasmic Reticulum Protein Homeostasis in Cancer: Friend or Foe.- IP3 Receptor Biology and Endoplasmic Reticulum Calcium Dynamics in Cancer.- Disruption of Endoplasmic Reticulum Proteostasis in Age-Related Nervous System Disorders.- Endoplasmic Reticulum Homeostasis and Stress Responses in Caenorhabditis elegans.- Tardigrada: An Emerging Animal Model to Study the Endoplasmic Reticulum Stress Response to Environmental Extremes.

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• Biologia Celular (citologia)
• Imunologia
• Oncologia
• Neurologia e neurofisiologia clínica

Endoplamatic Reticulum;Organelles of the Eukaryotic Cell;Calreticulin;Calcium Release;Cisternae;Cellular Calicum Homeostastis;Cell Signaling;Cellular Stress Responses;Membrane System;Non-mammalian Research Models;Organelle;Protein Quality Control;Protein Transport;Store-operated Calcium Entry