Systemic Effects of Advanced Cancer

Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications.- Part I. Systemic Regulation in Metastatic Disease.- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles.- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host.- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities.- Part II. Cachexia: A Debilitating Systemic Effect of Cancer.- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia.- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia.- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia.- Part III. Therapy-induced Muscle Wasting.- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia.- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy.- Part IV. Preventing and Targeting Cachexia in Cancer.- Chapter 10. New Developments in Targeting Cancer Cachexia.- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.

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• Biologia Celular (citologia)
• Oncologia
• Imunologia

systemic cancer effects;cachexia;cancer metabolism;Muscle wasting;tumour microenvironment;cancer metastasis;signaling in cachexia;chemotherapy;cancer-induced muscle wasting;skeletal muscle;cachexia treatment;cytokines;interleukin-6 IL-6;cachexia prevention;bone metastasis