Studying Ageing and Disease in Laboratory Mice

Part 1: Concepts in Ageing
1. An overview of ageing in laboratory mice and man - Paul Potter + others
2. Factors important in modelling ageing

Part 2: Assessing Ageing in Rodents
. Lifespan and Healthspan - Paul Potter and Ilaria Bellantuono
4. Phenotyping Ageing Laboratory Mice -Dan Ehninger
5. Frailty Indices - Susan Howlett
6. Resilience Challenges

Part 3: Available Models
7. Inbred, wild type and other strains
8. Progeroid Models -Sulev Koks
9. Modifications affecting Ageing - Caloric restriction, drugs, - JR, Dan Ehninger
10. Models of Multimorbidity
11. Models of Ageing Disease - Paul Potter + Others

Part 4: Experimental Plans
12. Breeding and maintaining cohorts - All
13. Factors influencing ageing cohorts - Dan Ehninger
14. Example protocols - All

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• Patologia e doenças dos animais
• Zoologia: Mamíferos

laboratory mice; ageing; healthspan; mouse models; Aging; Assessment of aging; Caloric restriction; Mechanisms of aging; Mouse models; Transposable elements