Organelle and Molecular Targeting

Preface. Acknowledgments. Editors. Contributors. SECTION ONE: INTRODUCTION: ORGAN, TISSUE, AND CELLULAR LOCALIZATION. Route of Administration, Distribution, and Tissue-Specific Challenges. Nanomedicine and Drug Delivery Approaches. Escaping Immune Clearance. Passive Drug Delivery, Mechanisms of Uptake, and Intracellular Trafficking. Tumor Targeting. Localizing Therapeutics to the Brain. Pulmonary Drug Delivery. Cardiovascular Drug Delivery. Localizing Therapeutics to the Gastrointestinal System. Targeting Immune Cells and Dysfunction. SECTION TWO: OVERCOMING CELLULAR BARRIERS. Overcoming the Plasma Membrane. Overcoming the Mucus Barrier. Directing Therapies to Lysosomes. Microtubule Targeting in Cancer Treatment. Localizing Therapeutics to the Endoplasmic Reticulum. Targeting Mitochondria. Directed Therapies to Nucleic Acid and Cytoplasmic RNA. Considerations for Engineering Nanoparticles for Achieving Subcellular Organelle Targeting. Index.

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• Pesquisa médica
• Farmacologia
• Biologia Celular (citologia)
• Biologia molecular
• Bioquímica
• Tecnologia farmacêutica
• Biotecnologia

Drug Delivery;Brain Targeted Drug Delivery;EVs;Clathrin Mediated Endocytosis;Endocytic Pathway;mRNA Vaccines;TNBC;Delivery Systems;1B Light Chain;Active Transport;ER Target;Late Endosomes;Endocytosis Pathways;Plasma Membrane;Nuclear Pore Complex;Mucin Dispersion;MTAs;Brain CSF Barrier;M1 Macrophage;ER Stress;ER Sheet;M1 Polarization;CMT;FLT3 Inhibitor;Clathrin Coated Vesicles