Insights into Human Neurodegeneration: Lessons Learnt from Drosophila

Chapter 1. Introduction to Drosophila as a model organism.- Chapter 2. Methods for creating fly models in order to understand molecular mechanism of neurological diseases.- Chapter 3. Neurodegeneration: Lessons learnt from forward genetic screens in Drosophila.- Chapter 4. Drosophila neural stem cells, a primer for understanding mammalian neurobiology.- Chapter 5. Understanding motor disorders using flies.- Chapter 6. Metabolic alterations amalgamated with neurodegenerative diseases.- Chapter 7. Notch signalling in neurodegenerative disease.- Chapter 8. Drosophila model of neurofibrillar tangles.- Chapter 9. Unraveling Alzheimer's disease using Drosophila.- Chapter 10. Modelling Human Parkinson's disease in fly.- Chapter 11. Post-translational modifications: A mystery to unravel Huntington's disease.- Chapter 12. Understanding the pathogenicity of non-coding RNA expansion associated neurodegenerative disorders.- Chapter 13. Expanding roles of RNA binding proteins in neurodegeneration.- Chapter 14. Hereditary Spastic Paraplegia Disease in Drosophila.- Chapter 15. Drosophila as a model system for the identification of pharmacological therapies in neurodegenerative diseases.

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• Biologia, ciências da vida
• Equipamentos científicos, experiências e técnicas
• Neurociências
• Biologia do desenvolvimento
• Biologia Celular (citologia)

Drosophila;Neurodegeneration;Molecular mechanisms;Genetic screen;Model system