Handbook of Mitochondrial Dysfunction
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portes grátis
Handbook of Mitochondrial Dysfunction
Ahmad, Shamim I.
Taylor & Francis Ltd
06/2019
480
Dura
Inglês
9781138336087
15 a 20 dias
1573
Descrição não disponível.
Contents
Preface ........................................................................................................................................................................... xi
Acknowledgment......................................................................................................................................................... xiii
About the Editor .......................................................................................................................................................... xv
Contributors ............................................................................................................................................................... xvii
SECTION I Introduction: Structure and Function of Mitochondria
Chapter 1 Mitochondrial Structure and Function ....................................................................................................... 3
Marcos Roberto de Oliveira
Chapter 2 Structure, Function and Evolutionary Aspects of Mitochondria ................................................................ 9
Puja Agarwal, Mehali Mitra, and Sujit Roy
Chapter 3 Mitochondrial Genome Damage, Dysfunction and Repair ........................................................................23
Kalyan Mahapatra, Sayanti De, and Sujit Roy
SECTION II Mitochondrial Dysfunction and Diseases
Chapter 4 Instability of Human Mitochondrial DNA, Nuclear Genes and Diseases ..................................................39
Katarzyna Tonska
Chapter 5 Kearns-Sayre Syndrome .............................................................................................................................55
Josef Finsterer
Chapter 6 Mitochondrial Dysfunction and Barth Syndrome......................................................................................61
Arianna F. Anzmann, Steven M. Claypool, and Hilary Vernon
Chapter 7 Mitochondrial Dysfunction in the Pathophysiology of Alzheimer's Disease ..............................................79
Isaac G. Onyango
Chapter 8 Mitochondrial Dysfunction in Multiple Sclerosis.......................................................................................87
Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bijak, and Michal Bijak
Chapter 9 Mitochondrial Dysfunction in Chronic Kidney Disease.............................................................................93
Maria V. Irazabal and Alfonso Eirin
Chapter 10 Mitochondrial Dysfunction in Breast Cancer: A Potential Target from the Bench to Clinical
Therapeutics.............................................................................................................................................103
Thalita Basso Scandolara, Leticia Madureira Pacholak, Thayse Fachin Cormanique, Rodrigo Kern,
and Carolina Panis
Chapter 11 Mitochondrial Dysfunction and DNA Methylation in Atherosclerosis ....................................................115
Silvio Zaina and Gertrud Lund
Chapter 12 Mitochondrial Dysfunction and Heart Diseases ......................................................................................127
Dao-Fu Dai
Chapter 13 The Role of Mitochondrial Dysfunction in Mitophagy and Apoptosis and Its Relevance to Cancer .......143
Jan Jezek
Chapter 14 Mitochondrial Dysfunction Linking Obesity and Asthma .......................................................................151
Naveen K. Bhatraju and Anurag Agrawal
Chapter 15 Mitochondrial Dysfunction and Hearing Loss.........................................................................................163
Maria de la Luz Arenas Sordo
Chapter 16 Superoxide Dismutase, Mitochondrial Dysfunction, and Neurodegenerative Diseases ............................171
Jahaun Azadmanesh and Gloria E. O. Borgstahl
Chapter 17 Role of Post-Translational Modifications of Mitochondrial Complex I in Mitochondrial Dysfunction
and Human Brain Pathologies .................................................................................................................191
Vismaya, Yogachar Chithra, and Muchukunte Mukunda Srinivas Bharath
Chapter 18 Heme Oxygenase-1 in Kidney Health and Disease: Perspective of Mitochondrial Homeostasis ..............205
Pu Duann, Elias A. Lianos, and Pei-Hui Lin
Chapter 19 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury ....................................217
David Blitzer, Borami Shin, Alvise Guariento, Pedro J. del Nido, and James D. McCully
Chapter 20 Mitochondrial Dysfunction in Diabetes ...................................................................................................231
Eric L. Johnson
Chapter 21 Clinical Manifestation of Mitochondrial Disorders in Childhood............................................................243
Martin Magner
Chapter 22 Mitochondrial Dysfunction and Epilepsies ..............................................................................................265
Bindu Parayil Sankaran and Arun B. Taly
Chapter 23 Mitochondrial Dysfunction and Allergic Disease.....................................................................................277
Kritika Khanna and Anurag Agrawal
SECTION III Factors Affecting Mitochondrial Function
Chapter 24 Role of Carnosic Acid in Protection of Brain Mitochondria ....................................................................293
Marcos Roberto de Oliveira
Chapter 25 Mitochondrial Dysfunction and Its Impact on Oxidative Capacity of Muscle .........................................309
Teet Seene
Chapter 26 The Effects of Resveratrol on the Brain Mitochondria.............................................................................319
Marcos Roberto de Oliveira
Chapter 27 Pathophysiology and Biomarkers of Mitochondrial Dysfunction Induced by Heavy Exercise .................335
Sergej M. Ostojic
Chapter 28 Mitochondrial Pathologies and Their Neuromuscular Manifestations .....................................................341
Carlos Ortez and Andres Nascimento
Chapter 29 Mitochondrial Stress and Cellular Senescence..........................................................................................361
Irene L. Tan and Michael C. Velarde
Chapter 30 Role of Mitochondrial Dysfunction in Human Obesity ...........................................................................379
David Albuquerque, Sara Silva, Daniel Alvarez-Vaca, Celia Aveleira, and Clevio Nobrega
Chapter 31 Roles of Melatonin in Maintaining Mitochondrial Welfare: Focus on Renal Cells...................................389
Feres Jose Mocayar Maron, Emiliano Diez, Russel J. Reiter, and Walter Manucha
Chapter 32 Mitochondrial Dysfunction Affecting the Peripheral Nervous System in Diabetic Neuropathy
and Avenues for Therapy..........................................................................................................................399
Jennifer Jossart, Taylor N. Dennis, and J. Jefferson P. Perry
Chapter 33 Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome................409
Qiaozhu Su and Hao Wang
SECTION IV Immunity and Toxicity
Chapter 34 Regulation of Antiviral Immunity by Mitochondrial Dynamics ..............................................................425
Mohsin Khan, Hasan Imam, and Saiful Anam Mir
Chapter 35 Mitochondrial Dysfunction, Immune Systems, Their Diseases, and Possible Treatments.........................443
Elise Jacquin, Eric Hervouet, and Michael Boyer-Guittaut
Chapter 36 Organophosphorus Compound-Induced Mitochondrial Disruption........................................................461
Alan J. Hargreaves
Chapter 37 Mitochondrial Dysfunction in Friedreich Ataxia .....................................................................................471
Rosella Abeti, Annalisa Baccaro, and Paola Giunti
Index............................................................................................................................................................................477
Preface ........................................................................................................................................................................... xi
Acknowledgment......................................................................................................................................................... xiii
About the Editor .......................................................................................................................................................... xv
Contributors ............................................................................................................................................................... xvii
SECTION I Introduction: Structure and Function of Mitochondria
Chapter 1 Mitochondrial Structure and Function ....................................................................................................... 3
Marcos Roberto de Oliveira
Chapter 2 Structure, Function and Evolutionary Aspects of Mitochondria ................................................................ 9
Puja Agarwal, Mehali Mitra, and Sujit Roy
Chapter 3 Mitochondrial Genome Damage, Dysfunction and Repair ........................................................................23
Kalyan Mahapatra, Sayanti De, and Sujit Roy
SECTION II Mitochondrial Dysfunction and Diseases
Chapter 4 Instability of Human Mitochondrial DNA, Nuclear Genes and Diseases ..................................................39
Katarzyna Tonska
Chapter 5 Kearns-Sayre Syndrome .............................................................................................................................55
Josef Finsterer
Chapter 6 Mitochondrial Dysfunction and Barth Syndrome......................................................................................61
Arianna F. Anzmann, Steven M. Claypool, and Hilary Vernon
Chapter 7 Mitochondrial Dysfunction in the Pathophysiology of Alzheimer's Disease ..............................................79
Isaac G. Onyango
Chapter 8 Mitochondrial Dysfunction in Multiple Sclerosis.......................................................................................87
Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bijak, and Michal Bijak
Chapter 9 Mitochondrial Dysfunction in Chronic Kidney Disease.............................................................................93
Maria V. Irazabal and Alfonso Eirin
Chapter 10 Mitochondrial Dysfunction in Breast Cancer: A Potential Target from the Bench to Clinical
Therapeutics.............................................................................................................................................103
Thalita Basso Scandolara, Leticia Madureira Pacholak, Thayse Fachin Cormanique, Rodrigo Kern,
and Carolina Panis
Chapter 11 Mitochondrial Dysfunction and DNA Methylation in Atherosclerosis ....................................................115
Silvio Zaina and Gertrud Lund
Chapter 12 Mitochondrial Dysfunction and Heart Diseases ......................................................................................127
Dao-Fu Dai
Chapter 13 The Role of Mitochondrial Dysfunction in Mitophagy and Apoptosis and Its Relevance to Cancer .......143
Jan Jezek
Chapter 14 Mitochondrial Dysfunction Linking Obesity and Asthma .......................................................................151
Naveen K. Bhatraju and Anurag Agrawal
Chapter 15 Mitochondrial Dysfunction and Hearing Loss.........................................................................................163
Maria de la Luz Arenas Sordo
Chapter 16 Superoxide Dismutase, Mitochondrial Dysfunction, and Neurodegenerative Diseases ............................171
Jahaun Azadmanesh and Gloria E. O. Borgstahl
Chapter 17 Role of Post-Translational Modifications of Mitochondrial Complex I in Mitochondrial Dysfunction
and Human Brain Pathologies .................................................................................................................191
Vismaya, Yogachar Chithra, and Muchukunte Mukunda Srinivas Bharath
Chapter 18 Heme Oxygenase-1 in Kidney Health and Disease: Perspective of Mitochondrial Homeostasis ..............205
Pu Duann, Elias A. Lianos, and Pei-Hui Lin
Chapter 19 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury ....................................217
David Blitzer, Borami Shin, Alvise Guariento, Pedro J. del Nido, and James D. McCully
Chapter 20 Mitochondrial Dysfunction in Diabetes ...................................................................................................231
Eric L. Johnson
Chapter 21 Clinical Manifestation of Mitochondrial Disorders in Childhood............................................................243
Martin Magner
Chapter 22 Mitochondrial Dysfunction and Epilepsies ..............................................................................................265
Bindu Parayil Sankaran and Arun B. Taly
Chapter 23 Mitochondrial Dysfunction and Allergic Disease.....................................................................................277
Kritika Khanna and Anurag Agrawal
SECTION III Factors Affecting Mitochondrial Function
Chapter 24 Role of Carnosic Acid in Protection of Brain Mitochondria ....................................................................293
Marcos Roberto de Oliveira
Chapter 25 Mitochondrial Dysfunction and Its Impact on Oxidative Capacity of Muscle .........................................309
Teet Seene
Chapter 26 The Effects of Resveratrol on the Brain Mitochondria.............................................................................319
Marcos Roberto de Oliveira
Chapter 27 Pathophysiology and Biomarkers of Mitochondrial Dysfunction Induced by Heavy Exercise .................335
Sergej M. Ostojic
Chapter 28 Mitochondrial Pathologies and Their Neuromuscular Manifestations .....................................................341
Carlos Ortez and Andres Nascimento
Chapter 29 Mitochondrial Stress and Cellular Senescence..........................................................................................361
Irene L. Tan and Michael C. Velarde
Chapter 30 Role of Mitochondrial Dysfunction in Human Obesity ...........................................................................379
David Albuquerque, Sara Silva, Daniel Alvarez-Vaca, Celia Aveleira, and Clevio Nobrega
Chapter 31 Roles of Melatonin in Maintaining Mitochondrial Welfare: Focus on Renal Cells...................................389
Feres Jose Mocayar Maron, Emiliano Diez, Russel J. Reiter, and Walter Manucha
Chapter 32 Mitochondrial Dysfunction Affecting the Peripheral Nervous System in Diabetic Neuropathy
and Avenues for Therapy..........................................................................................................................399
Jennifer Jossart, Taylor N. Dennis, and J. Jefferson P. Perry
Chapter 33 Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome................409
Qiaozhu Su and Hao Wang
SECTION IV Immunity and Toxicity
Chapter 34 Regulation of Antiviral Immunity by Mitochondrial Dynamics ..............................................................425
Mohsin Khan, Hasan Imam, and Saiful Anam Mir
Chapter 35 Mitochondrial Dysfunction, Immune Systems, Their Diseases, and Possible Treatments.........................443
Elise Jacquin, Eric Hervouet, and Michael Boyer-Guittaut
Chapter 36 Organophosphorus Compound-Induced Mitochondrial Disruption........................................................461
Alan J. Hargreaves
Chapter 37 Mitochondrial Dysfunction in Friedreich Ataxia .....................................................................................471
Rosella Abeti, Annalisa Baccaro, and Paola Giunti
Index............................................................................................................................................................................477
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
ZnPP Ix;Complex Iii;Mitochondrial Unfolded Protein Response;Mitochondrial DNA Deletion;Mitochondrial DNA Replication;Mitochondrial Fission Factor;Mitochondrial Dysfunction;Mitochondrial Fission;Mitochondrial DNA;Mitochondrial Biogenesis;Mitochondrial Dynamics;ATP Synthase;TCA Cycle;ATP Production;Progressive External Ophthalmoplegia;PEO;POLG Mutation;Mitochondrial ROS;Amp Activate Protein Kinase;Mitochondrial Fusion;Sh SY5Y Cell;mtDNA Deletions;mtDNA Depletion;Extracellular ATP;T2 Dm Patient
Contents
Preface ........................................................................................................................................................................... xi
Acknowledgment......................................................................................................................................................... xiii
About the Editor .......................................................................................................................................................... xv
Contributors ............................................................................................................................................................... xvii
SECTION I Introduction: Structure and Function of Mitochondria
Chapter 1 Mitochondrial Structure and Function ....................................................................................................... 3
Marcos Roberto de Oliveira
Chapter 2 Structure, Function and Evolutionary Aspects of Mitochondria ................................................................ 9
Puja Agarwal, Mehali Mitra, and Sujit Roy
Chapter 3 Mitochondrial Genome Damage, Dysfunction and Repair ........................................................................23
Kalyan Mahapatra, Sayanti De, and Sujit Roy
SECTION II Mitochondrial Dysfunction and Diseases
Chapter 4 Instability of Human Mitochondrial DNA, Nuclear Genes and Diseases ..................................................39
Katarzyna Tonska
Chapter 5 Kearns-Sayre Syndrome .............................................................................................................................55
Josef Finsterer
Chapter 6 Mitochondrial Dysfunction and Barth Syndrome......................................................................................61
Arianna F. Anzmann, Steven M. Claypool, and Hilary Vernon
Chapter 7 Mitochondrial Dysfunction in the Pathophysiology of Alzheimer's Disease ..............................................79
Isaac G. Onyango
Chapter 8 Mitochondrial Dysfunction in Multiple Sclerosis.......................................................................................87
Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bijak, and Michal Bijak
Chapter 9 Mitochondrial Dysfunction in Chronic Kidney Disease.............................................................................93
Maria V. Irazabal and Alfonso Eirin
Chapter 10 Mitochondrial Dysfunction in Breast Cancer: A Potential Target from the Bench to Clinical
Therapeutics.............................................................................................................................................103
Thalita Basso Scandolara, Leticia Madureira Pacholak, Thayse Fachin Cormanique, Rodrigo Kern,
and Carolina Panis
Chapter 11 Mitochondrial Dysfunction and DNA Methylation in Atherosclerosis ....................................................115
Silvio Zaina and Gertrud Lund
Chapter 12 Mitochondrial Dysfunction and Heart Diseases ......................................................................................127
Dao-Fu Dai
Chapter 13 The Role of Mitochondrial Dysfunction in Mitophagy and Apoptosis and Its Relevance to Cancer .......143
Jan Jezek
Chapter 14 Mitochondrial Dysfunction Linking Obesity and Asthma .......................................................................151
Naveen K. Bhatraju and Anurag Agrawal
Chapter 15 Mitochondrial Dysfunction and Hearing Loss.........................................................................................163
Maria de la Luz Arenas Sordo
Chapter 16 Superoxide Dismutase, Mitochondrial Dysfunction, and Neurodegenerative Diseases ............................171
Jahaun Azadmanesh and Gloria E. O. Borgstahl
Chapter 17 Role of Post-Translational Modifications of Mitochondrial Complex I in Mitochondrial Dysfunction
and Human Brain Pathologies .................................................................................................................191
Vismaya, Yogachar Chithra, and Muchukunte Mukunda Srinivas Bharath
Chapter 18 Heme Oxygenase-1 in Kidney Health and Disease: Perspective of Mitochondrial Homeostasis ..............205
Pu Duann, Elias A. Lianos, and Pei-Hui Lin
Chapter 19 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury ....................................217
David Blitzer, Borami Shin, Alvise Guariento, Pedro J. del Nido, and James D. McCully
Chapter 20 Mitochondrial Dysfunction in Diabetes ...................................................................................................231
Eric L. Johnson
Chapter 21 Clinical Manifestation of Mitochondrial Disorders in Childhood............................................................243
Martin Magner
Chapter 22 Mitochondrial Dysfunction and Epilepsies ..............................................................................................265
Bindu Parayil Sankaran and Arun B. Taly
Chapter 23 Mitochondrial Dysfunction and Allergic Disease.....................................................................................277
Kritika Khanna and Anurag Agrawal
SECTION III Factors Affecting Mitochondrial Function
Chapter 24 Role of Carnosic Acid in Protection of Brain Mitochondria ....................................................................293
Marcos Roberto de Oliveira
Chapter 25 Mitochondrial Dysfunction and Its Impact on Oxidative Capacity of Muscle .........................................309
Teet Seene
Chapter 26 The Effects of Resveratrol on the Brain Mitochondria.............................................................................319
Marcos Roberto de Oliveira
Chapter 27 Pathophysiology and Biomarkers of Mitochondrial Dysfunction Induced by Heavy Exercise .................335
Sergej M. Ostojic
Chapter 28 Mitochondrial Pathologies and Their Neuromuscular Manifestations .....................................................341
Carlos Ortez and Andres Nascimento
Chapter 29 Mitochondrial Stress and Cellular Senescence..........................................................................................361
Irene L. Tan and Michael C. Velarde
Chapter 30 Role of Mitochondrial Dysfunction in Human Obesity ...........................................................................379
David Albuquerque, Sara Silva, Daniel Alvarez-Vaca, Celia Aveleira, and Clevio Nobrega
Chapter 31 Roles of Melatonin in Maintaining Mitochondrial Welfare: Focus on Renal Cells...................................389
Feres Jose Mocayar Maron, Emiliano Diez, Russel J. Reiter, and Walter Manucha
Chapter 32 Mitochondrial Dysfunction Affecting the Peripheral Nervous System in Diabetic Neuropathy
and Avenues for Therapy..........................................................................................................................399
Jennifer Jossart, Taylor N. Dennis, and J. Jefferson P. Perry
Chapter 33 Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome................409
Qiaozhu Su and Hao Wang
SECTION IV Immunity and Toxicity
Chapter 34 Regulation of Antiviral Immunity by Mitochondrial Dynamics ..............................................................425
Mohsin Khan, Hasan Imam, and Saiful Anam Mir
Chapter 35 Mitochondrial Dysfunction, Immune Systems, Their Diseases, and Possible Treatments.........................443
Elise Jacquin, Eric Hervouet, and Michael Boyer-Guittaut
Chapter 36 Organophosphorus Compound-Induced Mitochondrial Disruption........................................................461
Alan J. Hargreaves
Chapter 37 Mitochondrial Dysfunction in Friedreich Ataxia .....................................................................................471
Rosella Abeti, Annalisa Baccaro, and Paola Giunti
Index............................................................................................................................................................................477
Preface ........................................................................................................................................................................... xi
Acknowledgment......................................................................................................................................................... xiii
About the Editor .......................................................................................................................................................... xv
Contributors ............................................................................................................................................................... xvii
SECTION I Introduction: Structure and Function of Mitochondria
Chapter 1 Mitochondrial Structure and Function ....................................................................................................... 3
Marcos Roberto de Oliveira
Chapter 2 Structure, Function and Evolutionary Aspects of Mitochondria ................................................................ 9
Puja Agarwal, Mehali Mitra, and Sujit Roy
Chapter 3 Mitochondrial Genome Damage, Dysfunction and Repair ........................................................................23
Kalyan Mahapatra, Sayanti De, and Sujit Roy
SECTION II Mitochondrial Dysfunction and Diseases
Chapter 4 Instability of Human Mitochondrial DNA, Nuclear Genes and Diseases ..................................................39
Katarzyna Tonska
Chapter 5 Kearns-Sayre Syndrome .............................................................................................................................55
Josef Finsterer
Chapter 6 Mitochondrial Dysfunction and Barth Syndrome......................................................................................61
Arianna F. Anzmann, Steven M. Claypool, and Hilary Vernon
Chapter 7 Mitochondrial Dysfunction in the Pathophysiology of Alzheimer's Disease ..............................................79
Isaac G. Onyango
Chapter 8 Mitochondrial Dysfunction in Multiple Sclerosis.......................................................................................87
Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bijak, and Michal Bijak
Chapter 9 Mitochondrial Dysfunction in Chronic Kidney Disease.............................................................................93
Maria V. Irazabal and Alfonso Eirin
Chapter 10 Mitochondrial Dysfunction in Breast Cancer: A Potential Target from the Bench to Clinical
Therapeutics.............................................................................................................................................103
Thalita Basso Scandolara, Leticia Madureira Pacholak, Thayse Fachin Cormanique, Rodrigo Kern,
and Carolina Panis
Chapter 11 Mitochondrial Dysfunction and DNA Methylation in Atherosclerosis ....................................................115
Silvio Zaina and Gertrud Lund
Chapter 12 Mitochondrial Dysfunction and Heart Diseases ......................................................................................127
Dao-Fu Dai
Chapter 13 The Role of Mitochondrial Dysfunction in Mitophagy and Apoptosis and Its Relevance to Cancer .......143
Jan Jezek
Chapter 14 Mitochondrial Dysfunction Linking Obesity and Asthma .......................................................................151
Naveen K. Bhatraju and Anurag Agrawal
Chapter 15 Mitochondrial Dysfunction and Hearing Loss.........................................................................................163
Maria de la Luz Arenas Sordo
Chapter 16 Superoxide Dismutase, Mitochondrial Dysfunction, and Neurodegenerative Diseases ............................171
Jahaun Azadmanesh and Gloria E. O. Borgstahl
Chapter 17 Role of Post-Translational Modifications of Mitochondrial Complex I in Mitochondrial Dysfunction
and Human Brain Pathologies .................................................................................................................191
Vismaya, Yogachar Chithra, and Muchukunte Mukunda Srinivas Bharath
Chapter 18 Heme Oxygenase-1 in Kidney Health and Disease: Perspective of Mitochondrial Homeostasis ..............205
Pu Duann, Elias A. Lianos, and Pei-Hui Lin
Chapter 19 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury ....................................217
David Blitzer, Borami Shin, Alvise Guariento, Pedro J. del Nido, and James D. McCully
Chapter 20 Mitochondrial Dysfunction in Diabetes ...................................................................................................231
Eric L. Johnson
Chapter 21 Clinical Manifestation of Mitochondrial Disorders in Childhood............................................................243
Martin Magner
Chapter 22 Mitochondrial Dysfunction and Epilepsies ..............................................................................................265
Bindu Parayil Sankaran and Arun B. Taly
Chapter 23 Mitochondrial Dysfunction and Allergic Disease.....................................................................................277
Kritika Khanna and Anurag Agrawal
SECTION III Factors Affecting Mitochondrial Function
Chapter 24 Role of Carnosic Acid in Protection of Brain Mitochondria ....................................................................293
Marcos Roberto de Oliveira
Chapter 25 Mitochondrial Dysfunction and Its Impact on Oxidative Capacity of Muscle .........................................309
Teet Seene
Chapter 26 The Effects of Resveratrol on the Brain Mitochondria.............................................................................319
Marcos Roberto de Oliveira
Chapter 27 Pathophysiology and Biomarkers of Mitochondrial Dysfunction Induced by Heavy Exercise .................335
Sergej M. Ostojic
Chapter 28 Mitochondrial Pathologies and Their Neuromuscular Manifestations .....................................................341
Carlos Ortez and Andres Nascimento
Chapter 29 Mitochondrial Stress and Cellular Senescence..........................................................................................361
Irene L. Tan and Michael C. Velarde
Chapter 30 Role of Mitochondrial Dysfunction in Human Obesity ...........................................................................379
David Albuquerque, Sara Silva, Daniel Alvarez-Vaca, Celia Aveleira, and Clevio Nobrega
Chapter 31 Roles of Melatonin in Maintaining Mitochondrial Welfare: Focus on Renal Cells...................................389
Feres Jose Mocayar Maron, Emiliano Diez, Russel J. Reiter, and Walter Manucha
Chapter 32 Mitochondrial Dysfunction Affecting the Peripheral Nervous System in Diabetic Neuropathy
and Avenues for Therapy..........................................................................................................................399
Jennifer Jossart, Taylor N. Dennis, and J. Jefferson P. Perry
Chapter 33 Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Metabolic Syndrome................409
Qiaozhu Su and Hao Wang
SECTION IV Immunity and Toxicity
Chapter 34 Regulation of Antiviral Immunity by Mitochondrial Dynamics ..............................................................425
Mohsin Khan, Hasan Imam, and Saiful Anam Mir
Chapter 35 Mitochondrial Dysfunction, Immune Systems, Their Diseases, and Possible Treatments.........................443
Elise Jacquin, Eric Hervouet, and Michael Boyer-Guittaut
Chapter 36 Organophosphorus Compound-Induced Mitochondrial Disruption........................................................461
Alan J. Hargreaves
Chapter 37 Mitochondrial Dysfunction in Friedreich Ataxia .....................................................................................471
Rosella Abeti, Annalisa Baccaro, and Paola Giunti
Index............................................................................................................................................................................477
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
ZnPP Ix;Complex Iii;Mitochondrial Unfolded Protein Response;Mitochondrial DNA Deletion;Mitochondrial DNA Replication;Mitochondrial Fission Factor;Mitochondrial Dysfunction;Mitochondrial Fission;Mitochondrial DNA;Mitochondrial Biogenesis;Mitochondrial Dynamics;ATP Synthase;TCA Cycle;ATP Production;Progressive External Ophthalmoplegia;PEO;POLG Mutation;Mitochondrial ROS;Amp Activate Protein Kinase;Mitochondrial Fusion;Sh SY5Y Cell;mtDNA Deletions;mtDNA Depletion;Extracellular ATP;T2 Dm Patient
