Epigenetics and Proteomics of Leukemia

Epigenetics and Proteomics of Leukemia

A Synergy of Experimental Biology and Computational Informatics

Borutinskait?e, Veronika; Navakauskien?e, R?uta; Matuzevi?cius, Dalius; Navakauskas, Dalius

Springer Nature Switzerland AG

09/2021

406

Dura

Inglês

9783030687076

15 a 20 dias

863

Descrição não disponível.
Introduction.- Epigenetics in Leukemia.- Genetic and Epigenetic Alterations in Leukemia.- Epigenetic Modifiers and Their Inhibitors in Leukemia Treatment.- Chromatin Remodeling during Leukemia Cell Proliferation and Differentiation.- DNA Methylation and Epigenetic Regulation.- Chromatin Functional Regulation by Histone Modification.- Approaches to Epigenetic Treatment of Leukemia.- Proteomics in Leukemia.- Proteome in Leukemic vs. Differentiated Leukemia Cells.- Protein Phosphorylation in Leukemia.- Computational Methods for Proteome Analysis.- 2DE Fractionation and Visualization.- Proteomic Data Processing.- Proteomic Data Analysis.- Image Acquisition and Data Analysis.- Image Acquisition and Data Analysis.- Protein Localization in Leukemia.- Protein Translocation into the Nucleus during Leukemia Cell Differentiation.- Protein Visualization in Leukemic Cells.- Computational Methods for Protein Localization Estimation.- Fluorescent Image Processing.- Fluorescent Image Acquisition and Analysis.- Future Therapy in Leukemia.- Index.
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Epigenetics;Proteomics;Leukemia;Chromatin;2DE;Protein Visualization;Computational Biology