ENZYMES: Catalysis, Kinetics and Mechanisms
portes grátis
ENZYMES: Catalysis, Kinetics and Mechanisms
Punekar, Narayan S.
Springer Verlag, Singapore
12/2024
628
Dura
9789819781782
Pré-lançamento - envio 15 a 20 dias após a sua edição
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1. Enzymes -Their place in Biology.- 2. Enzymes - Historical aspects.- 3. Hallmarks of an enzyme catalyst.- 4. Origins of enzyme catalytic power.- 5. Which enzyme uses what tricks?.- 6. Structure and catalysis: Conformational flexibility and protein motion.- 7. On enzyme nomenclature and classification.- 8. Chemical Kinetics: Fundamentals.- 9. Concepts of equilibrium and steady state.- 10. ES Complex and Pre-steady-state Kinetics.- 11. Principles of Enzyme Assays.- 12. Good Kinetic Practices.- 13. Quantification of Catalysis and Measures of Enzyme Purity.- 14. Henri-Michaelis-Menten Equation.- 15. More Complex Rate Expressions.- 16. Enzyme Kinetic Data: Collection and Analysis.- 17. Approaches to Kinetic Mechanism: An Overview.- 18. Analysis of Initial Velocity Patterns.- 19. Enzyme Inhibition Analyses.- 20. Irreversible Inhibitions.- 21. Reversible Inhibitions.- 22. Alternate Substrate (Product) Interactions.- 23. pH Studies with Enzymes.- 24. Isotopes in Enzymology.- 25. Isotope Effects in Enzymology.- 26. From Kinetic Data to Mechanism and Back.- 27. Chemical Reactivity and Molecular Interactions.- 28. Acid-Base Chemistry and Catalysis.- 29. Nucleophilic Catalysis and Covalent Reaction Intermediates.- 30. Phosphoryl Group Chemistry and Importance of ATP.- 31. Enzymatic Oxidation-Reduction Reactions.- 32. Carboxylations and Decarboxylations.- 33. Electrophilic Catalysis and Amino Acid Transformations.- 34. Free Radicals and radical enzymology.- 35. Integrating Kinetic and Chemical Mechanisms: A Synthesis.- 36. Enzyme Inhibitor Design: Drug Discovery.- 37. Exploiting enzymes: Technology and applications.- 38. Regulation of Enzyme Activity.- 39. In Vitro Versus In Vivo: Concepts and Consequences.- 40. Future of Enzymology: An Appraisal.
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Enzyme cataysis;Kinetic mechanism;Chemical mechanism;Metabolic regulation;Enzyme kinetics;Protein-Ligand Interactions;Open Access
1. Enzymes -Their place in Biology.- 2. Enzymes - Historical aspects.- 3. Hallmarks of an enzyme catalyst.- 4. Origins of enzyme catalytic power.- 5. Which enzyme uses what tricks?.- 6. Structure and catalysis: Conformational flexibility and protein motion.- 7. On enzyme nomenclature and classification.- 8. Chemical Kinetics: Fundamentals.- 9. Concepts of equilibrium and steady state.- 10. ES Complex and Pre-steady-state Kinetics.- 11. Principles of Enzyme Assays.- 12. Good Kinetic Practices.- 13. Quantification of Catalysis and Measures of Enzyme Purity.- 14. Henri-Michaelis-Menten Equation.- 15. More Complex Rate Expressions.- 16. Enzyme Kinetic Data: Collection and Analysis.- 17. Approaches to Kinetic Mechanism: An Overview.- 18. Analysis of Initial Velocity Patterns.- 19. Enzyme Inhibition Analyses.- 20. Irreversible Inhibitions.- 21. Reversible Inhibitions.- 22. Alternate Substrate (Product) Interactions.- 23. pH Studies with Enzymes.- 24. Isotopes in Enzymology.- 25. Isotope Effects in Enzymology.- 26. From Kinetic Data to Mechanism and Back.- 27. Chemical Reactivity and Molecular Interactions.- 28. Acid-Base Chemistry and Catalysis.- 29. Nucleophilic Catalysis and Covalent Reaction Intermediates.- 30. Phosphoryl Group Chemistry and Importance of ATP.- 31. Enzymatic Oxidation-Reduction Reactions.- 32. Carboxylations and Decarboxylations.- 33. Electrophilic Catalysis and Amino Acid Transformations.- 34. Free Radicals and radical enzymology.- 35. Integrating Kinetic and Chemical Mechanisms: A Synthesis.- 36. Enzyme Inhibitor Design: Drug Discovery.- 37. Exploiting enzymes: Technology and applications.- 38. Regulation of Enzyme Activity.- 39. In Vitro Versus In Vivo: Concepts and Consequences.- 40. Future of Enzymology: An Appraisal.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
