Drug Target Selection and Validation

Drug Target Selection and Validation

Bellera, Carolina L.; Scotti, Marcus T.

Springer Nature Switzerland AG

05/2022

257

Dura

Inglês

9783030958947

15 a 20 dias

582

Descrição não disponível.
Drug discovery paradigms: target-based drug discovery.- Drug discovery paradigms: phenotypic-based drug discovery.- Target Identification Approaches in Drug Discovery.- Introduction to target validation.- Structure-based binding pocket detection and druggability assessment.- Network-Based Target Identification.- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We?.- Metabolic Control Analysis for drug target selection against human diseases.- Progress on open chemoinformatic tools for drug discovery.
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early drug discovery;drug discovery;druggability;network pharmacology;precision medicine;drug design;metabolic analysis;genetic based drug targeting