Voltage-Gated Calcium Channels

Voltage-Gated Calcium Channels

Weiss, Norbert; Zamponi, Gerald Werner

Springer International Publishing AG

11/2022

710

Dura

Inglês

9783031088803

15 a 20 dias

1533

Descrição não disponível.
1. Measuring and manipulating calcium.- 2. Structure, function and subunit assembly of VGCC.- 3. Splice variation and RNA editing of VGCCs.- 4. Mechanisms of calcium channel permeation.- 5. Regulation by beta subunits .- 6. Regulation by alpha2 delta subunits.- 7. VGCCs in invertebrates.- 8. Modulation by GPCRs and second messengers.- 9. Trafficking of VGCCs.- 10. Calcium regulation.- 11. Calcium channel complexes with other channels.- 12. Regulation of gene transcription by VGCCs.- 13. Lessons from knock-out and knock-in mice.- 14. VGCCs and synaptic transmission.- 15. Cardiovascular syste.- 16. Calcium channels and exocytosis in chromaffin cells.- 17. Calcium channels in the pancreas in health and disease.- 18. Skeletal muscle system.- 19. Auditory and visual systems.- 20. Calcium channels and pain transmission.- 21. Migraine.- 22. Epilepsy.- 23. Psychiatric disorders.- 24. Parkinson's disease.-25. Reproductive system.- 26. Cancer.- 27. Molecular determinants of VGCC pharmacology.- 28. Interactions with peptide toxins.- 29. Clinical pharmacology and drug discovery.
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Activation;Biophysics;Peptide;cardiovascular;genes;distribution;physiology;regulation;the role of CA+2;Cyclic Nucleotide-Gated channels;P2X Receptors;Calcium channel discovery;Ca2+ Signaling and storage;calcium channel genes;epilepsy;hypertension