Viral Fitness and Evolution

Theoretical analysis of the evolution of viral populations in sequence space, and empirical fitness landscapes.- Self-organized maps to derive fitness landscapes from deep sequencing data.- Mutations to overcome viral resistance in plants.- The role of recombination in the generation of new begomovirus phenotypes.- Plant virus adaptation to new hosts.- Viral fitness, host interactions, and resistance to antiviral agents.- Viral fitness and evolution of hepatitis C virus.- Population dynamics and fitness variations of hemorrhagic RNA viruses.- Coronavirus genome sequences, variation, and disease implications.- Epilogue: viral populations from a theoretical and experimental perspective.

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• Evolução
• Genética (não médica)
• Virologia (não médica)

Quasispecies;Host adaptation;Pathogen emergence;Virus-host interactions;Viral infections;Genomic mutation;Plant and animal viruses;Coronaviruses;Begomovirus;Hemorrhagic RNA viruses