Oncogene-Induced Senescence
portes grátis
Oncogene-Induced Senescence
Methods and Protocols
Evangelou, Konstantinos; Gorgoulis, Vassilis G.; Cavinato-Nascimento, Maria
Springer-Verlag New York Inc.
04/2025
365
Dura
9781071644256
Pré-lançamento - envio 15 a 20 dias após a sua edição
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In Situ and In Silico Methods for Senescence Identification in Human Liver Diseases.- Current Methodologies to Assess Cellular Senescence in Cancer.- Selective Sorting of Senescent Cell Subpopulations Compatible with Downstream Genomics Pipelines.- Detection and Characterization of Senescent Cells with Flow Cytometry.- Detecting Senescence in T Cells by Flow Cytometry Using the SA-?-galactosidase Assay.- The DNA Damage Response as an Auxiliary Indicator of Senescence in Cancer: A User-Friendly Toolkit of Markers and Detection Methods.- Precise Mapping of Physiological DSBs Using In-Suspension Break Labelling In Situ and Sequencing (sBLISS).- Detecting Telomeric DNA Damage by Immuno-Telo FISH.- Combined In Situ Transcriptomic and Immunofluorescence to Assess the Effects on DNA Damage and Innate Immune Responses Induced by Bacterial Genotoxin in In Vivo Models.- Two-Replication Round Telomere Strand-Specific Chromosome Orientation Fluorescent In Situ Hybridization.- Identification of Oncogene-Induced Senescence-Associated MicroRNAs.- Global Proteomic Profiling to Unravel Lipofuscin's Protein Repertoire.- Electron Microscopy to Visualize and Quantify Mitochondrial Structure and Organellar Interactions in Cultured Cells during Senescence.- Isolation and Characterization of EVs Containing Mitochondria from OIS Cells.- Isolation and Characterization of Endothelial Colony Forming Cells (ECFC): Studying Endothelial Senescence for Translational Studies and for Personalized Medicine.- In Vitro Modeling of Vascular Senescence.- Studying Cellular Senescence Using the Model-Organism Drosophila melanogaster.- C. elegans as a Screening Platform for Anti-Aging Compounds.- Natural Product-Derived Senotherapeutics: Extraction and Biological Evaluation Techniques.
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OIS;High throughput machine learning;Oncology;Computational analysis;Oncogenic signaling
In Situ and In Silico Methods for Senescence Identification in Human Liver Diseases.- Current Methodologies to Assess Cellular Senescence in Cancer.- Selective Sorting of Senescent Cell Subpopulations Compatible with Downstream Genomics Pipelines.- Detection and Characterization of Senescent Cells with Flow Cytometry.- Detecting Senescence in T Cells by Flow Cytometry Using the SA-?-galactosidase Assay.- The DNA Damage Response as an Auxiliary Indicator of Senescence in Cancer: A User-Friendly Toolkit of Markers and Detection Methods.- Precise Mapping of Physiological DSBs Using In-Suspension Break Labelling In Situ and Sequencing (sBLISS).- Detecting Telomeric DNA Damage by Immuno-Telo FISH.- Combined In Situ Transcriptomic and Immunofluorescence to Assess the Effects on DNA Damage and Innate Immune Responses Induced by Bacterial Genotoxin in In Vivo Models.- Two-Replication Round Telomere Strand-Specific Chromosome Orientation Fluorescent In Situ Hybridization.- Identification of Oncogene-Induced Senescence-Associated MicroRNAs.- Global Proteomic Profiling to Unravel Lipofuscin's Protein Repertoire.- Electron Microscopy to Visualize and Quantify Mitochondrial Structure and Organellar Interactions in Cultured Cells during Senescence.- Isolation and Characterization of EVs Containing Mitochondria from OIS Cells.- Isolation and Characterization of Endothelial Colony Forming Cells (ECFC): Studying Endothelial Senescence for Translational Studies and for Personalized Medicine.- In Vitro Modeling of Vascular Senescence.- Studying Cellular Senescence Using the Model-Organism Drosophila melanogaster.- C. elegans as a Screening Platform for Anti-Aging Compounds.- Natural Product-Derived Senotherapeutics: Extraction and Biological Evaluation Techniques.
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