Multiple Testing Problems in Pharmaceutical Statistics

Multiple Testing Problems in Pharmaceutical Statistics

Tamhane, Ajit C.; Dmitrienko, Alex; Bretz, Frank

Taylor & Francis Ltd

01/2023

322

Mole

Inglês

9781032477701

15 a 20 dias

600

Descrição não disponível.
Multiplicity Problems in Clinical Trials: A Regulatory Perspective. Multiple Testing Methodology. Multiple Testing in Dose Response Problems. Analysis of Multiple Endpoints in Clinical Trials. Gatekeeping Procedures in Clinical Trials. Adaptive Designs and Confirmatory Hypothesis Testing. Design and Analysis of Microarray Experiments for Pharmacogenomics. Bibliography.
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Multiplicity Adjustment;FWER;multiplicity;Interim Analyses;adjustment;Fallback Procedure;Multiple Testing Procedures;hypothesis;Intersection Hypotheses;procedure;Multiple Endpoints;endpoints;Secondary Endpoints;error;Multiple Testing Problems;rate;Gatekeeping Procedures;clinical;OLS Procedure;trial;Multiple Comparison Procedures;Holm Procedure;Co-primary Endpoints;Coprimary Endpoints;Hochberg Procedure;Dunnett Procedure;GLS Procedure;Composite Biomarker;Conditional Error Rates;Elementary Hypotheses;Error Rate Function;Hommel Procedure;Adaptive Designs;Parallel Gatekeeping