Molecular Signaling in Spermatogenesis and Male Infertility

Primordial germ cells: Origin, migration and testicular development. DNA methylation, imprinting and gene regulation in germ cells. Testicular stem cells, spermatogenesis and infertility. Testicular germ cell apoptosis and spermatogenesis. Hormonal regulation of spermatogenesis. GH-IGF1 axis in spermatogenesis and male fertility. Retinoic acid signaling in spermatogenesis and male (in)fertility. Testosterone signaling in spermatogenesis, male fertility and infertility. Wnt signaling in spermatogenesis and male infertility. MAPK signaling in spermatogenesis and male infertility. TGF-? signaling in testicular development, spermatogenesis, and infertility. Notch signaling in spermatogenesis and male (in)fertility. Hedgehog signaling in spermatogenesis and male fertility. mTOR signaling in spermatogenesis and male infertility. JAK-STAT pathway: Testicular development, spermatogenesis and fertility. PI3K signaling in spermatogenesis and male infertility. Spermatogenesis, heat stress and male infertility

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• Embriologia
• Endocrinologia
• Medicina reproductiva
• Urologia e medicina urológica
• Infertilidade e fertilização
• Saude pública e medicina preventiva

Apical Ectoplasmic Specializations;Cyst Stem Cells;Sertoli Cells;Tubulobulbar Complexes;Basal Ectoplasmic Specializations;Seminiferous Tubules;Seminiferous Epithelium;SSCs;Hub Cells;Germ Cells;Germ Cell Apoptosis;Peritubular Myoid Cells;Stem Cell Renewal;BMP Ligand;Adluminal Compartment;DNA Methylation;Spermatogonial Differentiation;Round Spermatids;Undifferentiated Spermatogonia;Primordial Germ Cells;Stem Cell;Jak Stat Pathway;Jak Stat Signaling;Notch Signaling;DNA Methylation Mark