Modeling Inhibitors of Matrix Metalloproteinases

Modeling Inhibitors of Matrix Metalloproteinases

Jha, Tarun

Taylor & Francis Ltd

05/2025

474

Mole

Inglês

9781032300610

Pré-lançamento - envio 15 a 20 dias após a sua edição

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Part A: Fundamentals of molecular modeling

Chapter 1

2D-QSAR studies: Regression and classification-based QSAR studies

Chapter 2

3D-QSAR studies: CoMFA, CoMSIA and Topomer CoMFA methods

Chapter 3

Other modeling approaches: Pharmacophore mapping, molecular docking and molecular dynamic simulation studies

Part B: Matrix metalloporteinases and their inhibitors

Chapter 4

Collagenases and their inhibitors

Chapter 5

Gelatinases and their inhibitors

Chapter 6

Stromelysins and their inhibitors

Chapter 7

Matrilysins and their inhibitors

Chapter 8

Membrane-type MMPs and their inhibitors

Chapter 9

Other MMPs and their inhibitors

Part C: Modeling of MMP inhibitors

Chapter 10

Modeling inhibitors of Collagenases

Chapter 11

Modeling inhibitors of Gelatinases

Chapter 12

Modeling inhibitors of Stromelysins

Chapter 13

Modeling inhibitors of Matrilysins

Chapter 14

Modeling inhibitors of membrane-type MMPs

Chapter 15

Modeling inhibitors of other MMPs

Part D: Conclusion and Future Perspective

Chapter 16

Conclusion and Future Perspectives
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Matrix metalloproteinases (MMPs);Matrix metalloproteinases inhibitors (MMPIs);Molecular modeling;Ligand-based drug designing;Structure-based drug designing;Drug discovery