Insight on Genotoxicity

Insight on Genotoxicity

Kalyani, Gunjan; Shukla, Shiv Shankar; Gidwani, Bina; Pandey, Ravindra Kumar

Taylor & Francis Ltd

10/2024

170

Mole

9780367557478

Pré-lançamento - envio 15 a 20 dias após a sua edição

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Introduction to Genotoxicity. Genotoxicity and DNA Repair. Consequence of DNA Damage. Mechanism of Genotoxicity. Impact of ICH Guidelines on Genotoxicity Testing: Dogmatic Obligation for Innovation Drug Discovery and Development. Genotoxicity Prediction. Computational prediction. Computational prophecy of Genotoxicity with models. Bioindicator of Genotoxicity: The Allium cepa Test. Genotoxicity appraisal of Nano sized material and particles. Genotoxicity Evaluation in Phytopharmaceuticals: Perspective Review. Deterrence of Genotoxicity: Brief Perspective. Genotoxic and non-genotoxic chemicals for review of the performance improved genotoxicity. Genotoxic impurities in Pharmaceuticals. Genotoxicity and carcinogenicity predictive software systems. Poultry manure Induced DNA Damage. Expert opinion on the basis of the content and easy understandable rundown for the reader.
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DNA Damage;Allium Cepa Test;mutagenicity analyses;GIs;genotoxicity assessment;Structural Alert;genetic toxicity mechanisms;DNA Repair;drug discovery;Genotoxicity Tests;ICH guidelines;Comet Assay;QSAR Model;DNA Reactive;Ich Guideline;LDH Assay;QSAR;Genetic Toxicity;DNA Repair System;DNA Lesion;Micronucleus Test;Specific DNA Damage;Genotoxicity Assay;EURL ECVAM;DNA Structure;Double Strand Break Repair;Direct DNA Damage;DNA Reactive Carcinogen;Aristolochic Acids;Potential GTIs