Handbook of Laboratory Animal Science

Handbook of Laboratory Animal Science

Essential Principles and Practices

Schapiro, Steven J.; Hau, Jann

Taylor & Francis Ltd

05/2021

994

Dura

Inglês

9781138341807

15 a 20 dias

2912

Descrição não disponível.
Animal research ethics. Alternatives: refinement, reduction and replacement of animal uses in the life sciences. Laboratory animal genetics and genetic quality control. Experimental design and statistical analysis. Behavioral needs and management of laboratory animals. Welfare assessment and humane endpoints. Impact of the biotic and abiotic environment on animal experiments. Animal research facility design and equipment considerations for conventional, barrier, and containment housing systems. Genetically modified mice. Microbiological status. Laboratory animal nutrition in routine husbandry, and experimental and regulatory studies. Common nonsurgical techniques and procedures. Laboratory animal analgesia, anesthesia and euthanasia. Surgery: basic principles and procedures. Applications of implantable radio telemetry in small laboratory animals. Physiological, hematological, and clinical chemistry. Postmortem procedures animal models for diabetes: basic principles and management. Animal models of spinal cord injury. Animal models in pain research. Rodents, sheep and non-human primates as models for human pregnancy and fetal development. Animal models in biodefense research. Animal models in neuroscience. Animal models for psychological disorders. Animal models for human behavior. Animal models of cardiovascular disease. Animal models in pharmacology and toxicology. Animal models in mycology. Animal models in oral health sciences. Animal models of hearing loss, tinnitus, and hyperacusis. Animal models for otolaryngological disorders. Animal models for eye diseases. Animal models in aids research. Models of human cancer. An overview of global legislation, regulations and policies. Laboratory animal science and service organizations. Education and training. Assessment of animal care and use programs. Reduction and refinement applied to animal models
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Laboratory Animal Science;Animal Care;animal behavior;Animal Facilities;Spinal Cord;3Rs;Laboratory Animal;animal models;Basilar Membrane;animal research;ES Cell;animal experimentation;OECD Tg;Animal discomfort;Laboratory Animal Medicine;Hair Cells;Reoviridae;Animal Studies;Positive Reinforcement Training;Radioisotope containment;European Laboratory Animal Science Associations;IACUC Member;VAPs;Kilham Rat Virus;Locomotor Activity;Animal Welfare Regulations;IVC;Cancer Induced Bone Pain;Nonhuman Primates;DPOAE Amplitude;LCMV;Cynomolgus Monkey;HIV-1 Infection