Formulating Poorly Water Soluble Drugs

Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs.- Optimizing the Formulation of Poorly Water-Soluble Drugs.- Solid-State Techniques for Improving Solubility.- Mechanical Particle-Size Reduction Techniques.- Co-solvent and Complexation Systems.- Injectable Formulations of Poorly Water-Soluble Drugs.- Lipid-Based Formulations.- Structured Development Approach for Amorphous Systems.- Melt Extrusion.- Spray-Drying Technology.- Pharmaceutical Cryogenic Technologies.- Precipitation Technologies for Nanoparticle Production.- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs.- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.

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• Bioquímica
• Farmacologia
• Pesquisa médica

bioavailability;lipophilic;solubility;dissolution;formulation development;nanoparticle processes;amorphous systems;drug delivery;route-specific challenges;drug dosage design