Essentials of Pharmatoxicology in Drug Research, Volume 1

Essentials of Pharmatoxicology in Drug Research, Volume 1

Toxicity and Toxicodynamics

Tekade, Rakesh Kumar

Elsevier Science Publishing Co Inc

03/2023

752

Mole

Inglês

9780443158407

15 a 20 dias

Descrição não disponível.
1. Understanding Pharmacotoxicology
2. Mechanisms of Drug Toxicity and Relevance to Pharmaceutical Development
3. Omics in Mechanistic and Predictive Toxicology
4. Role of Micro RNAs in Toxicology
5. Exosomes as Mediators of Chemical-Induced Toxicity
6. Types of Cellular Responses to Chemical Toxicants
7. Tissue Repair as A Key Determinant in Toxicant-Induced Injury
8. Role Of "Toxicant-Induced Loss of Tolerance? in the Emergence of Disease
9. Computer-Aided Technologies in Drug Discovery and Toxicity Prediction
10. Adverse Outcome Pathway for Chemical Toxicity
11. Toxicokinetics and Organ-Specific Toxicity
12. Dose Selection for Toxicity Studies
13. Tissue-Based Models as A Replacement for Animal Models in Toxicity Testing
14. Medication Error and its Toxicity Connection
15. Idiosyncratic Toxicity
16. Toxicological Risk Assessment
17. Clinical Detoxification of the Body
18. Principles of Management of Acute Poisoning
19. Predicting Toxicity and Modes of Toxic Action from Chemical Structure
20. Toxicity Labels
21. Toxic Potential Indicator
22. Aquatic Toxicology
23. Concept of Pharmacotherapy and Managed Care in Clinical Interventions
24. Psychopharmacology in Late Life: Key Challenges and Opportunities
25. Regulatory Agencies for Toxicity Studies
26. Key Challenges for Toxicologists in the 21st Century
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Toxicology; risk assessment; drug safety; mechanistic toxicology; predictive toxicology; toxicodynamics; toxicoepigenetics; pharmacotoxicology; clinical interventions; acute poisoning; chemical and food toxicants; toxicity tests; Predicting toxicity; toxicity tests; adverse outcome pathways