CPP, Cell-Penetrating Peptides

CPP, Cell-Penetrating Peptides

Langel, UElo

Springer International Publishing AG

10/2024

556

Mole

9783031387333

15 a 20 dias

Descrição não disponível.
1. Introduction.- 2. Classes and applications of CPP.- 3. CPP selection, prediction and in silico analysis.- 4. Labeling of CPPs.- 5. Methods for CPP functionalization with oligonucleotides.- 6. Additional (gene therapeutic) platforms.- 7. Protein delivery and mimicry.- 8. General targeting strategies.- 9. Targeting specific barriers.- 10. Methods for molecular imaging, detection and visualization of CPPs.- 11. Methods for structural studies of CPPs.- 12. Kinetics.- 13. Toxicity and immune response.- 14. Cell-translocation mechanisms of CPPs.- 15. Clinical trials and commercialization using CPPs.- 16. Therapeutic potential of CPPs.- 17. CPP functionalized nanoparticles.- 18. Concluding remarks.
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Protein / peptide transduction domain;Trojan peptide;Drug delivery;CPP uptake;CPP processing